Week 10 College Football Schedule & Predictions — 2025

Every game with kickoff, TV, live score, and Gridpex's model pick. Tap a matchup for the full prediction, odds, and advanced-stat breakdown.

UTEP vs. Kennesaw State

Pick: KENN

20–33

James Madison vs. Texas State

Pick: JMU

52–20

Jacksonville State vs. Middle Tennessee

Pick: JXST

24–21

Florida International vs. Missouri State

Pick: MOST

21–28

Tulane vs. UTSA

Pick: TULN

26–48

Marshall vs. Coastal Carolina

Pick: MRSH

27–44

Memphis vs. Rice

Pick: MEM

38–14

North Carolina vs. Syracuse

Pick: SYR

27–10

Sam Houston vs. Louisiana Tech

Pick: LT

14–55

UCF vs. Baylor

Pick: UCF

3–30

West Virginia vs. Houston

Pick: HOU

45–35

Army vs. Air Force

Pick: ARMY

20–17

Duke vs. Clemson

Pick: CLEM

46–45

Vanderbilt vs. Texas

Pick: TEX

31–34

UAB vs. UConn

Pick: CONN

19–38

Navy vs. North Texas

Pick: UNT

17–31

Penn State vs. Ohio State

Pick: OSU

14–38

Miami vs. SMU

Pick: MIA

20–26

Buffalo vs. Bowling Green

Pick: BGSU

28–3

Rutgers vs. Illinois

Pick: ILL

13–35

Arizona State vs. Iowa State

Pick: ISU

24–19

East Carolina vs. Temple

Pick: ECU

45–14

Louisville vs. Virginia Tech

Pick: LOU

28–16

New Mexico vs. UNLV

Pick: UNLV

40–35

Pittsburgh vs. Stanford

Pick: PITT

35–20

New Mexico State vs. Western Kentucky

Pick: WKU

16–35

Fresno State vs. Boise State

Pick: BOIS

30–7

Indiana vs. Maryland

Pick: IU

55–10

Notre Dame vs. Boston College

Pick: ND

25–10

Louisiana vs. South Alabama

Pick: USA

31–22

Old Dominion vs. UL Monroe

Pick: ODU

31–6

Texas Tech vs. Kansas State

Pick: TTU

43–20

Michigan State vs. Minnesota

Pick: MINN

20–23

Delaware vs. Liberty

Pick: LIB

30–59

Georgia vs. Florida

Pick: UGA

24–20

Virginia vs. California

Pick: UVA

31–21

Central Michigan vs. Western Michigan

Pick: WMU

21–24

Oklahoma State vs. Kansas

Pick: KU

21–38

Mississippi State vs. Arkansas

Pick: ARK

38–35

Wyoming vs. San Diego State

Pick: SDSU

7–24

Purdue vs. Michigan

Pick: MICH

16–21

Arizona vs. Colorado

Pick: COLO

52–17

South Carolina vs. Ole Miss

Pick: MISS

14–30

Oklahoma vs. Tennessee

Pick: TENN

33–27

Wake Forest vs. Florida State

Pick: FSU

7–42

Kentucky vs. Auburn

Pick: AUB

10–3

Washington State vs. Oregon State

Pick: WSU

7–10

USC vs. Nebraska

Pick: USC

21–17

Georgia Tech vs. NC State

Pick: GT

36–48

Arkansas State vs. Troy

Pick: TROY

23–10

Cincinnati vs. Utah

Pick: UTAH

14–45

Hawai'i vs. San José State

Pick: SJSU

38–45