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Pittsburgh vs. Louisville Prediction, Odds & Pick

Prediction, odds and the model's read

L&N Federal Credit Union StadiumConference game

Our model's read

Model win probability
LOU 64%
Model line
LOU −5.7
Gridpex modelPITT 36% · LOU 64%
Pick LouisvilleModel line LOU −5.7

Scouting report

2026 projection · last season, roster and staff

Neither side projects a clear way in. Pittsburgh and Louisville rate within touching distance on every unit matchup here, closest at staying out of the backfield — on this evidence it comes down to the things a season profile cannot see.

The two teams

Pittsburgh

balanced

Pittsburgh is in year 12 under Pat Narduzzi, whose offenses have been balanced. The strengths are defensive, led by 5th at defending the run. The way in is 111th at staying out of the backfield.

On fourth down he goes for it about as often as his peers do from the same spots (−0.9%). Against what the expected-points model recommends he is −28.3% — the profession as a whole is negative on this.

Pittsburgh has played 2 games against an average slate, adjusted for here. That football carries about 0% of what is below; the rest is still the preseason projection.

Projected strengths

  • Defenserunning it
    #5
    projected
  • Defensethe push the line gets
    #5
    projected
  • Defensefirst and second down
    #11
    projected

Projected soft spots

  • Offensegetting stopped at the line
    #111
    projected

Louisville

heavily pass-leaning

Louisville throws it: Jeff Brohm's offenses have been heavily pass-leaning across 10 seasons. The strengths are on both sides of the ball, led by 14th at moving the ball on the ground. The way in is 113th at staying out of the backfield.

On fourth down he goes for it about as often as his peers do from the same spots (−2.2%). Against what the expected-points model recommends he is −35.9% — the profession as a whole is negative on this.

Louisville has played 2 games against a soft slate, adjusted for here. That football carries about 0% of what is below; the rest is still the preseason projection.

Projected strengths

  • Offensemoving the ball on the ground
    #14
    projected
  • Defensesurviving second and twelve
    #15
    projected
  • Defensethrowing it
    #19
    projected

Projected soft spots

  • Offensegetting stopped at the line
    #113
    projected

Ranks are national. Nothing here is last season's number — carrying one forward is measurably worse than saying nothing — and in-season figures are adjusted for who was actually played. This describes the matchup; it is not a prediction and not a pick.

Head coaches only — there is no free feed for coordinators, so on a program where the head coach does not call the offense this describes the staff he hired. Play-calling identity is a style, not a grade: throwing more than the situations warrant is not better than throwing less than they warrant.

Pregame line
Pregame total
Model line
LOU −5.7
Projected total

Model prediction

how the number is built
Power rating (Elo)
LOU 1668
PITT 1678
Projected spread
LOU -5.7
incl. home edge
Model pick
LOU
64% to win
Market spread
sportsbook line
Model vs market
Agrees
aligned w/ market
Win prob: model / mkt
64%
LOU (no market)

Our model simulates the game drive by drive from each side's opponent-adjusted efficiency (LOU Elo 1668, PITT Elo 1678 for reference), with home-field advantage. That projects LOU -5.7 (64% to win), essentially in line with the market.

Why that percentage is worth reading: across 604 graded in-season games, the calls this model put near 58% came in at 58.2%. The full calibration table is published, bin by bin. Early in the season the cold-start path runs instead and calibrates less well (Brier 0.2028 against 0.1889).

Model as of Sep 1 · through week 1 · drive simulation

Where the game is won

2026 national rank · right is better

offensethe defense it faces

  • Moving the ball

    PITT48th80thLOU
    LOU10th43rdPITT
  • Through the air

    PITT6th119thLOU
    LOU9th93rdPITT
  • On the ground

    PITT98th69thLOU
    LOU36th3rdPITT
  • Staying on the field

    PITT64th53rdLOU
    LOU34th29thPITT
  • Taking care of it

    PITT1st46thLOU
    LOU1st108thPITT

Each bar runs from last in the country on the left to 1st on the right. The filled span is the gap between the offense and the defense it faces.

Season form — 2026

nationally ranked
PITT2026 season · national rank shownLOU
480.531st
Total yards / game
552.010th
6.548th
Yards / play
8.210th
346.06th
Passing yards / game
341.09th
134.598th
Rushing yards / game
211.036th
42.9%64th
3rd down %
50.0%34th
247.527th
Yards allowed / game
370.597th
26.9%29th
3rd down % allowed
33.3%53rd
+141st
Turnover margin
+315th
6.562nd
Penalties / game
8.0106th

The matchup, in context

series history + adjusted profiles
The series22 meetings since 1976

The series is level at 1111 · Louisville has won 2 straight · 27% have been one-possession games

Opponent-adjusted profile2026
PITT LOU
+11.1 (#33)CORE overall+11.3 (#31)
+3 / -8offense / defense+8 / -3
3.00points / drive2.85
0.86allowed / drive3.15
26%three-and-outs31%
+3pass over expected-9

Bold is the side ahead. CORE strips the situation from every play and solves the schedule out across the league, so these compare two teams that never met.

Pro

Key matchups

The analyst read: each team's offense splits crossed against the opponent's defense, with the edges called out.

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FAQ

Who will win Pittsburgh vs. Louisville?

Gridpex's model favors Louisville with a 64% win probability.

What's the predicted spread for Pittsburgh vs. Louisville?

The model projects Louisville by 5.7.

What time is Pittsburgh vs. Louisville and what channel is it on?

Time TBD, at L&N Federal Credit Union Stadium.

Where this number comes from. Every projection on this page is produced by the same model, run before kickoff on opponent-adjusted efficiency, power ratings and situational data — walk-forward validated on eleven seasons and never adjusted after the fact. How the model works →

Model estimates for informational and entertainment purposes only. Not betting advice. 21+. If you or someone you know has a gambling problem, call 1-800-GAMBLER. Data: CollegeFootballData.